Severe contiguous perianal Crohn's disease
نویسندگان
چکیده
CD: Crohn’s disease INTRODUCTION Crohn’s disease (CD) is an idiopathic inflammatory bowel disease that is characterized by noncaseating granulomas that occur in the gastrointestinal tract. This disease is chronic, incurable, and prone to relapse. CD is frequently associated with skin and mucous membrane lesions. The skin is among the most common sites for extraintestinal involvement in CD. Estimated incidence ranges from 22% to 44% and includes distant cutaneous (metastatic) CD, contiguous perianal CD, oral CD, reactive skin findings (including erythema nodosum and pyoderma gangrenosum), and nutritional skin changes. The site of involvement can influence lesion morphology. Contiguous cutaneous CD distinguishes from metastatic CD, as it extends directly from the gastrointestinal tract. Lesions that appear on the legs often present as intact inflammatory papules and plaques, whereas those involving intertriginous and genital skin usually ulcerate owing to the propensity for maceration in these sites. We describe a severe and extensive case of CD with perianal involvement contiguous to an anal CD lesion.
منابع مشابه
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